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Experience with downstream purification operations and filtration, chromatography, or similar unit operations is an advantage. Whether you are considering starting a family, need help paying for emergency back up care or summer camp, looking for mental health resources, planning for your financial future, or supporting your favorite charity with a matching contribution, CSL Seqirus has many benefits to help achieve your goals.
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Practical experience in supporting/execution of bioprocess operations such as Chromatography, TFF, depth filtration, and continuous centrifugation with a strong experience in 1 area. Summary: Vaxcyte is looking for an energetic and talented Sr. Associate Engineer to contribute to the Polysaccharide Downstream Pilot Plant function within the CMC team.
$107,000 - $123,000 a yearFull-timeExpandApply NowActive JobUpdated 3 days ago - UpvoteDownvoteShare Job
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We are seeking a Scientist to join our Downstream Process Development Department - Process Sciences in Gaithersburg, MD. Qualified individuals will play a role in downstream process development; scale up, new technologies, and technical support of cGMP manufacturing for protein particle vaccines.
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Process development and manufacturing experience includes mammalian and/or microbial cell culture and scale up, the isolation and purification of proteins, antibodies, etc., extensive experience with product recovery (depth filtration, centrifugation, MF), TFF (UF/DF), chromatography (Affinity, IonX, HPT, HIC.
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Offer critical assistance of harvest equipment includes tanks, centrifuges and harvest filtration skids, cleaning equipment and other support systems such as CIP and COP. Must have experience in upstream/downstream bioprocesses and equipment.
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We are seeking an Associate Scientist to join our Downstream Process Development group in Gaithersburg, MD. Qualified individuals will be responsible for hands-on execution of downstream chromatography and filtration processes in support of process development, scale-up, process characterization activities, and technical support of cGMP manufacturing for proteins, nanoparticles, and virus-like particle (VLP) based vaccines.
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Perform shake flask culture, cell banking, fermentation, harvest clarification, normal and tangential flow filtration, homogenization, conjugation, chromatography techniques and/or formulation as needed.
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Profound understanding of bioreactor operations, aseptic techniques, upstream processing, and/or strong knowledge of tangential flow filtration, We are in search of a proficient and seasoned Manufacturing Manager or Supervisor with expertise in GMP (Good Manufacturing Practice) environments, particularly in overseeing cell culture and downstream processing operations.
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Provide job responsibilities listed below for Downstream Processing including but not limited to: Chromatography, Viral Filtration, and UF/DF. Direct knowledge of design and resolving issues with GMP Biopharmaceutical Production facility equipment/systems such as cell culture reactors, centrifugation, chromatography, tangential flow filtration as well as other equipment needed to support these processes such as autoclaves, clean in place (CIP) systems, washers, clean steam, water for injection, etc.
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Performing downstream operations such as normal flow filtration, tangential flow filtration, homogenization, lyophilization, chromatography, and centrifugation. For one of our Top Direct Global Pharmaceutical Client that is Merck Pharmaceuticals.
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Execute downstream technology strategies from bioreactor recovery, chromatography column purification, impurity removal, viral inactivation and filtration, UF/DF, and sterile filtration.
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The Senior Scientist I will play a key role in the developing downstream purification process development for various modalities such as mAbs, ADCs, bio-specifics, gene therapy, etc. Develop recovery and purification process that utilizes clarification, chromatography, and membrane filtration technologies for monoclonal antibodies, bio-specifics and antibody drug conjugates (ADC.
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Processing experience includes but not limited to: Chromatography, writing/using unicorn methods, Tangential Flow Filtration, Aseptic processing, bulk drug substance and drug product operations.
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A thorough understanding and working knowledge of the principles of purification and filtration processes is essential, with solid hands-on downstream process experience with chromatography systems, such as AKTA, and tangential flow (UFDF) filtration is required.
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The Scientist, Downstream Process Development in MSAT will work in a matrix team management environment with global engineers and scientists to achieve robust and scalable purification processes to support 2nd generation processes, late-stage programs, and life-cycle management.
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