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Upstream Knowledge of recombinant protein expression, metabolic pathways, biochemistry, and cell culture Understanding of basic bioreactor principles, mass transfer kinetics Understanding of cell & molecular biology Downstream Sound scientific knowledge of protein properties and purification.
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The co-op will work in a laboratory setting on a project related to protein purification process characterization and protein drug substance stability. Job Overview: The 2023 Co-Op will work in the downstream process development group of the drug substance function in Specialty Care Manufacturing Science and Analytical Technology (MSAT.
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Support drug candidate design optimization, selection, validation, and stability study throughout pre-clinical and clinical purification process development for antibody/protein. Ph. D.; MS in Protein Science, Biochemistry, Biophysics, or a related field (Ph. D., new graduates welcome); 5+ years (MS) of relevant pharmaceutical or biotech experience.
$90,000 - $120,000 a yearExpandApply NowActive JobUpdated Today - UpvoteDownvoteShare Job
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Development of upstream techniques and downstream purification of recombinant proteins. – M.S. microbiology, biochemistry, chemical engineering, bioprocess engineering or a related field.
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Knowledge and experience with large scale protein purification, nucleic acid purification, and other chromatography application processes. Education: MS degree in biotechnology, analytical chemistry, material science, polymer science, chemistry, chemical engineering, biochemistry or related field.
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Downstream Manufacturing: Conduct the protein purification process, encompassing tasks such as dialysis, filtration, diafiltration, large-scale buffer preparation, centrifugation, and chromatography.
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Additional skills to support downstream characterization as needed would be beneficial and could include: protein expression and purification using FPLC systems and biophysical characterization methods (SEC-MALS, DSF, and biosensor techniques including BLI and SPR.
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3 + years of experience in Process Engineering related to biochemical engineering and/or protein biochemistry, scale-up principles and manufacturing of biologics (cGMP) Upstream and/or Downstream process knowledge and hands on cell culture and/or purification.
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We utilize the latest software and automation to develop low, mid, and high throughput methods for protein and nucleic acid purification, enzyme kinetics and biophysical characterization.
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The ability to rationally design and optimize purification processes, characterize enzymes, and interpret complex data sets based on a strong understanding of protein biochemistry.
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Experience working with protein purification. Participate in/drive fermentation and/or purification of proteins/VLPs at lab and pilot scale. A bachelor’s degree in a relevant scientific discipline (biochemistry, chemistry, biology), life sciences.
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Upstream and/or Downstream process knowledge and hands on cell culture and/or purification pilot/clinical/commercial experience with regard to the manufacture of a biological drug substance.
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The Engineer/Scientist, Protein Development is responsible for research and process development in our enzyme program using conventional fermentation and purification methods. Collaborate with the biochemistry and molecular biology team on the enzyme of interest characteristics and peculiarities to adapt the most effective and efficient fermentation, DSP, and formulation strategy.
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Balletic Foods is a California based company working towards a sustainable food system by combining science and technology to create new sources of animal-free protein. If you are passionate about using biotechnology to build sustainable new sources of protein, join our team of scientists and entrepreneurs to change the worlds food system.
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Passionate about protein purification (including chromatography, bioprocess filtration, scale up, and optimization) and harnessing the power of enzymes to solve challenging real-world problems in the healthcare industry.
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