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The expectation is that the prospective postdoctoral researcher has basic level experience and interest in protein biochemistry work and experience with various biophysical techniques, ideally including structural biology tools that may include dipolar EPR spectroscopy, NMR spectroscopy, or Cryo-EM.
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The Cancer Center supports more than 200 ongoing clinical trials and has also invested significantly in research infrastructure including a new Cancer Research Building to be completed in 2024, state-of-the-art cryo-EM facility to be completed in 2023, and expansion of a mass spectrometry facility with installation of several new mass spectrometers in 2023.
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We are looking for candidates with biochemistry experience and a strong background in molecular and cell biology interested in using structural biology (single-particle and/or in situ cryo-EM.
$70,000 - $77,500 a yearFull-timeExpandApply NowActive JobUpdated 3 months ago - UpvoteDownvoteShare Job
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The SMC is integrated into a community of Institutionally-funded laboratories and innovation centers at St. Jude, each with their own dedicated staff, including the Cryo-EM Center, the Protein Technology Center, the Cell and Tissue Imaging Center, The Center for Bioimage Informatics, The Center for Applied Bioinformatics, the Center of Excellence for Data-driven Discovery and the Center for Advanced Genome Engineering (CAGE.
$114,400 - $216,320 a yearFull-timeExpandApply NowActive JobUpdated 8 days ago - UpvoteDownvoteShare Job
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Maintaining multiple 1000+ core high performance compute clusters designed to support genomics, molecular dynamics, cryo-EM analysis, proteomics, phylogenetics, and AI/ML research. Maintaining multiple 1000+ core high performance compute clusters designed to support genomics, molecular dynamics, cryo-EM analysis, proteomics, phylogenetics, and AI/ML research.
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Previous experience with cryo-EM, X-ray crystallography and biochemistry is preferred. The focus of the work will be on structure determination by cryo-EM (specimen preparation, data collection, data processing and analysis) and assay development for complementing our structural analyses.
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The institute is equipped for every step of the translational research process and houses a MAGNETOM Terra 7 Tesla (7T) MRI scanner, PET/CT, Cryo-EM and high-resolution electron microscopy, Clinical Translational Science Unit, Integrated informatics and data analytics spaces, Good Manufacturing Practice (GMP) spaces for pilot-scale manufacturing, and clean rooms for tissue engineering and device fabrication.
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We use high resolution electron cryo-microscopy (cryo-EM) and image processing to explore the molecular design of large, multicomponent supramolecular assemblies. We use high resolution electron cryo-microscopy (cryo-EM) and image processing to explore the molecular design of large, multicomponent supramolecular assemblies.
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The new cryo-EM facility is part of a strategic growth plan at UNL and complements existing strengths in X-ray crystallography, biophysics, and computation at UNL. Expertise in cryo-EM, X-ray crystallography, or computational structural biology.
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Scientific Researcher Responsibilities may include, but is not limited toConduct independent research, using structural biology techniques such as Cryo EM and X-ray crystallography, in combination with biochemical and functional assays to study complex biological mechanisms.
$47,500 - $65,400 a year depends on experienceFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Creating, maintaining, and reviewing Infrastructure as Code (IaC) using Ansible, Terraform, Python, and other scripting languages to manage High Performance Computing clusters across multiple sites. FULLY REMOTE -ideally EST or Central time zones.
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The Titan Krios Cryo-EM, complete with a Falcon4i detector, facilitates high-resolution imaging. This collaboration leverages specialized equipment for high-throughput metabolomics, characterization of microbial biofilm, host-microbiome interaction, and microbial ecology.
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We also have access to high-end 300kV Krios TEMs at several NIH and DOE-funded cryo-EM centers in the United States. Experience in cryo-EM would be a plus but is not required, as the lab will provide training.
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In this lab, we explore how different sensory membrane proteins work using advanced methods like single particle cryo-EM and patch-clamp electrophysiology. While experience in electrophysiology or Cryo-EM is helpful, it's not mandatory.
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In addition, we have access to additional Rutgers Cryo-EM and Cryo-ET instrumentation, including a 200kV Talos Arctica microscope, an Aquilos 2 FIB - SEM microscope, and a Leica Cryo- CLEM system located in on the Rutgers-Piscataway, NJ campus.
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