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The incumbent can identify, troubleshooting and leading the resolution of operational and equipment problems as they arise in the large-scale Bioreactor and Media Preparation areas with minimum supervision and effective communication to management.
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You would be responsible for working jointly with your upstream colleagues to link the bioreactor to the purification process. Required Skills: Buffer formulation, lab equipment operation such as Akta Avant, peristaltic pumps, pressure sensors, pH probes, pipet operation, UV spectrophotometry Experimental design with proteins Theory of Protein ion exchange and affinity chromatography or affinity precipitation Desired Skills: Fundamental and practical understanding of downstream unit operations Arduino programming and building prototypes Experience with GMP equipment design and use of data management systems.
ExpandApply NowActive JobUpdated 8 days ago - UpvoteDownvoteShare Job
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Perform cell culture and bioreactor operations at multiple scales. This position requires technical expertise in bioreactor operations, cell biology and knowledge of initiating batch records, protocols, investigations and other technical documents.
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Major responsibilities include routing sampling of cell culture experiments at various scales from shake flasks to bench-top bioreactors, setting up and taking down bioreactors before and after experiments, daily bioreactor sampling, and data entry.
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1+ years of experience with bioreactor cell culture process development. Experimental execution may include cell seeding, cell counting, bioreactor sampling, media exchange, cell harvesting, cell cryopreservation, immunostaining, and cell analytics.
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The ideal candidate will have a Grade V Wastewater Treatment Plant Operator Certification issued by the State of California, experience working with Membrane Bioreactor (MBR), Biological Nutrient Removal Process (BNR), Co-digestion of Organics, Microsoft software applications, Supervisory Control and Data Acquisition System, Process Control Data Base, Computerized Maintenance Management Systems and be able to supervise, motivate, and delegate crews working the various treatment processes.
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Specific equipment/systems that we are using include Cellmate roller bottle robot, 20L/50L wave bioreactor, Cytiva 200L & 500L single use bioreactor, TCU’s, BSC’s, roller racks, incubators and disposable technology systems.
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In-depth knowledge and deep understanding of mammalian cell-culture processes including molecular biology & cell culture engineering concepts, media design, bioreactor scale-up, mass transfer, bioreactor control, single use and stainless bioreactor systems.
$274,635 - $355,410 a yearFull-timeExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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The position is responsible for internal process development work, translating small scale experiments, which generate fundamental process understanding, into bioreactor systems which can be scaled up according to program requirements.
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Prior experience with bioreactor fermentations, including shake flasks and Sartorius Ambr® 250 bioreactor system. Prior experience with bioreactor fermentations, including shake flasks and Sartorius Ambr® 250 bioreactor system.
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Experience with culture of mammalian cells in small -scale and large-scale bioreactor systems and associated control strategies and automation. Experience interpreting cell therapy-related data, including flow cytometry, growth rates.
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Operate general manufacturing equipment in strict accordance with SOPs to complete tasks as noted above as well as large scale bioreactor operations, critical small or large volume sterile fills, and aseptic manipulation of cell cultures.
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Tasks to be completed may include fermentation, protein purification, solvent extractions, tissue culture, preparation of bulk solutions, aseptic fills of buffers, filling and labeling of vials under sterile and non-sterile conditions, routine buffer and media preparation, filtration, vial preparation and sterilization.
ExpandApply NowActive JobUpdated 20 days ago - UpvoteDownvoteShare Job
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Usa-manufacturing associate ii (manufacturing/quality) 1st shift. Min 1-3 Years of experience in Pharmaceutical Manufacturing. skills: SOP, MS-WORD, MS-EXCEL, MS-Powerpoint, GMP (Good Manufacturing Practice.
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The leader will drive the development of highly productive robust commercial fed-batch and perfusion processes leveraging strong scientific principles in medium development, cell metabolism, bioreactor engineering, and design of experiment.
Full-timeExpandApply NowActive JobUpdated 6 days ago
bioreactor job
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