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Must have hands-on experience analyzing DNA/RNA by a variety of techniques (e.g. IP-RP, IEX, LC-fluor, multi-modal LC, etc. Hands on experience developing and troubleshooting analytical methods applied to complex and heterogenous systems (e.g. HPLC/UPLC, capillary electrophoresis, cryoTEM, NMR, MALS, DLS, NTA, etc.
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Relevant hands-on lab experience in mammalian cell culture or protein purification. Basic understanding of protein chromatography, filtration or cell culture principles; hands-on experience with mammalian cell culture, and/or purification operations is a plus.
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Hands on experience with photolithography equipment, thin film measurement and characterization equipment, thin film deposition equipment for atomic layer deposition (ALD). Hands on experience with epitaxial film deposition and chemical mechanical polishing.
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Hands-on experience in next-generation sequencing, e.g. Illumina, Oxford Nanopore or PacBio platforms with various sample types, including purified DNA, microbial, fresh and FFPE tissue material, blood, etc.
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Hands-on lab experience in one of the following areas: DNA assembly, plasmid creation and amplification, analytical assay development for DNA/RNA, and NGS. Prepare detailed development documents and provide hands-on training to operators allowing for successful handoff of automation platforms.
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Knowledge/hands-on experience in oligonucleotide lipid nanoparticle delivery, production and purification of short and large oligonucleotides, protein engineering and process development are a plus, but not required.
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Hands-on experience with digital and analog electronics for instrumentation (microcontroller, DACs, etc.) We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all.
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Required: Extensive, hands-on experience with molecular biology methods, cellular assays and mammalian cell culture. Self-motivated, disciplined, and passionate about hands-on work in the lab.
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Hands-on in vivo model experience preferred, if no experience, must be open to learning. Hands-on experience with flow cytometry, neutralization assays and other cell-based functional assays preferred.
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Possess hands-on experience in analyzing DNA/RNAs or oligos using techniques such as ELISA, qPCR, ddPCR, flow cytometry, western blot, and other methods, with method development experience in mRNA/gRNA related DS/DPs.
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The successful candidate will have a strong hands-on background in wet lab biology to support nanomedicine-related research including but not limiting to nanoparticle formulation, flow cytometry, molecular endpoints, bioconjugate chemistry, in vitro assays, gel-based characterization and cell-based assays.
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Hands-on experience with tangential flow filtration (TFF) of protein solutions is desirable; BS (3+ years relevant experience) or MS degree (1-3 years relevant experience) in Pharmaceutical Sciences, Chemical Engineering, Chemistry, Biology, Bioengineering, or a related field.
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Hands-on experience with aspects of cell therapy manufacturing process preferred (cell culture, gene editing, magnetic selection, etc.) Become quickly adept at identifying current bottlenecks and opportunities through hands-on independent and collaborative investigations.
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Strong understanding of protein biochemistry with hands on experience performing biochemical and biophysical assays. BS with 5+ years of experience or MS with 3+ years of experience in Chemistry, Chemical Biology, Biochemistry, Bioengineering, or related discipline.
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MS or PhD in Biological, Biochemistry, Bioengineering, or related life sciences field with a strong scientific background and at least 8 years of relevant experience. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law.
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