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Hands experience on molecular biology, biochemistry, and cell biology techniques, such as molecular cloning, cell culture, DNA/RNA transfection, virus transduction, RNA isolation, real-time PCR, immunoblot, ELISA, MSD multiplex assay, cell viability assay, enzyme activity assay, etc.
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Experience and interest in assay development (in vitro/ex vivo/in vivo) This is a unique opportunity to work with world-class technologists innovating in cutting edge molecular biology and compute approaches to realize the potential of a novel protein engineering platform.
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The Molecular Assay Development team is seeking an accomplished (Senior) Scientist to join our team within the Cellular Therapy Analytical Development (CTAD) organization. Expert knowledge of and hands-on experience developing and optimizing analytical methods using molecular biology techniques, including various PCR-based methods and/or next-generation sequencing.
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Learn how to assess various assay readouts through different techniques (flow cytometry, Incucyte, MSD, ELISA, microscopy) This position will be laboratory-based, working directly with a team of scientists within Immuno-Oncology, Biology.
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PhD with 2+ years of industry experience in molecular assay development, or MS/MA in Molecular Biology or similar with 5+ years of related experience, or BS/BA with 10+ years of related experience.
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The successful candidate will have the opportunity to work with a stellar team of AAV experts and drive multiple innovative vector biology research projects. AS, BS, or MS degree completed (or near completion) in Biology, Molecular Biology, Cell Biology, Biochemistry, Immunology, Oncology or related discipline with 1-2 yrs of relevant research experience preferred.
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B.S. degree in biology or biochemistry with course work emphasizing molecular biology, cell biology, and/or virology. The Quality Control Analyst will work within the QC team, testing gene therapy products utilizing cell-based assays (Potency assay) in support of clinical and commercial lot release and stability activities.
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Experience sourcing and placing talent in areas relevant to early-stage research, including Platform development, Molecular Biology, Next Gen sequencing, genomics, and assay development. Recruiting Practice Director, Discovery Biology (Pharma & BioTech.
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The successful candidate will have hands-on experience with cell-based in-vitro potency assays, SDS-PAGE, Automated Western blot assays, enzyme activity measurements, protein extraction, purification, and quantification methods.
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In addition, review and approve CTL assay development and validation reports, relevant sections of clinical documents pertaining to AAV and RNA analytical testing and documentation for submission to regulatory agencies.
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This position is responsible for the technology platform screening, development, qualification, and transfer of molecular biology-based analytical methods; The (Senior) Scientist will have extensive hands-on experience in assay development; PhD with 2+ years of industry experience in molecular assay development, or MS/MA in Molecular Biology or similar with 5+ years of related experience, or BS/BA with 10+ years of related experience.
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Good knowledge of molecular biology and/or biochemistry and/or next-generation sequencing (NGS) and genomics. this position requires exposure to and expertise in areas of cutting-edge molecular biology, NGS technology, bioinformatics/biostatistics, and regulatory affairs.
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Biology techniques (Protein, DNA and RNA isolations, Western blot, qRT-PCR , Flow Cytometry ) The incumbent will be responsible for drug screening, cell-based assay development, and biomarker discovery.
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You will have the opportunity to maintain process excellence for a state-of-the art NGS infectious disease diagnostic assay by assisting in an established in-house manufacturing process. Strong molecular biology skills; e.g. DNA/RNA purification, nucleic acids hybridization, PCR, qPCR.
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The (Senior) Scientist will have extensive hands-on experience in assay development; possess excellent communication skills; and be able to work with cross-functional teams in order to effectively transfer analytical methods, as wells as maintain and troubleshoot existing methods.
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