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Mosaic teams provide comprehensive, end-to-end discovery services, including program assessment and strategy development; program management; antibody discovery and optimization; protein production, purification, and characterization; protein engineering; biochemical and cellular assay development; formulation, stability and developability studies; bioanalytical (PK and PD) assay development; and candidate-validating pharmacology.
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Collaborate with project team members (Project Management, Discovery Biology, Chemistry, Chemistry Manufacturing and Control, Regulatory), and groups within Translational Sciences (Bioanalytical, Toxicology, Translational Pharmacology, and Clinical Pharmacometrics) to generate relevant DMPK data to enable knowledge and data integration to inform and guide target validation, biomarker selection, and candidate advancement.
$129,500 - $191,500 a yearFull-timeExpandApply NowActive JobUpdated 7 days ago - UpvoteDownvoteShare Job
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At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases.
$240,000 - $400,000 a yearFull-timeExpandApply NowActive JobUpdated 2 months ago - UpvoteDownvoteShare Job
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First-hand knowledge of and experience with assays relevant for cell therapies including flow cytometry, IHC, qPCR, anti-therapeutic antibody assessment, T-cell antigen specific response assays (ELISPOT, flow based, tetramer, etc.
ExpandApply NowActive JobUpdated 6 days ago - UpvoteDownvoteShare Job
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As part of our mission, TRACTION is focused on partnering with our internal drug discovery engine (IACS, ORBIT, Biologics Development and Cell Therapies) and a growing list of external Partners (Boehringer Ingelheim, Taiho, Blueprint Medicines, Schr dinger and Obsidian) to discover and develop the next generation of small-molecule targeted therapies, antibody therapeutics and cell therapies, all driven by the needs we see in our patients.
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This position is a key member of the development team, executing clinical drug development activities by evaluating the clinical pharmacology of antibody therapeutics in an excellent organization that focused primarily, but not exclusively, on immune-inflammatory diseases.
$150,000 - $190,000 a yearFull-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Cellular and/or biochemical assays for antibody drug candidates screening, biological function evaluation in immuno-oncology and oncology drug discovery program. SparX Biopharmaceutical Corp. is a research-based development-stage biopharmaceutical company, dedicated to the mission of “strengthening human immunity using robust antibody therapies” through the discovery and development of innovative immuno-oncology agents.
ExpandApply NowActive JobUpdated 5 days ago - UpvoteDownvoteShare Job
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The successful candidate is expected to be a bench associate scientist and will use a wide range of techniques in antibody discovery, screening and characterization from lead identification, optimization, and clinical candidate selection.
$97,400Full-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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FibroGen recently expanded its research and development portfolio to include antibody-drug conjugate (ADC) and immuno-oncology product candidates for the treatment of solid tumors. Pamrevlumab, an anti-CTGF fully human monoclonal antibody, is in clinical development for the treatment of metastatic pancreatic cancer and locally advanced unresectable pancreatic cancer (LAPC.
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Capable of independently authoring and delivering ADME and Clinical Pharmacology sections of regulatory submissions. Understanding of bioanalytical techniques and methods for measuring drug levels and anti-drug antibody responses.
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Spearhead the development, execution, and analysis of in vivo pharmacology, PK/BD, and toxicology studies. Hold a PhD (or Master's) in Pharmacology, Pharmaceutical Sciences, Oncology, Toxicology, or a related field, with at least 2 years of pertinent experience (or 5+ years for non-PhD candidates), or possess an equivalent blend of industry expertise in preclinical drug discovery and development.
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Preferred: Master's degree in Biology, Biochemistry, Molecular Biology, Cell Biology, Enzymology, Pharmacology, Chemistry or related field. Required: Bachelor's degree in Biology, Biochemistry, Molecular Biology, Cell Biology, Enzymology, Pharmacology, Chemistry or related field.
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BS/MS in Biology, Pharmacology, Animal Science or related field is preferred. Driven by science and passionate about advancing patient care, we are translating potentially revolutionizing new insights on immuno-normalization into a pipeline of innovative antibody candidates with first-in-class and best-in-class potential.
Full-timeExpandApply NowActive JobUpdated 7 days ago - UpvoteDownvoteShare Job
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The Behavioral Pharmacology Research Unit is seeking a Research Program Coordinator who reports to the Research Program Supervisor. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing.
$16.42 - $22.57Full-timeExpandApply NowActive JobUpdated 2 days ago - UpvoteDownvoteShare Job
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Lead the lab through the development and execution of preclinical pharmacology immunoassays & models evaluating therapeutic antibody candidates. This position will be a critical lab-based role designing and executing immunology assays defining the pharmacology of lead antibody candidates.
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